OUR SOLUTIONS FOR YOUR RESEARCH
Casc4de is engaged in a new project IPANEMA
supported by ADEME, The French Agency for Ecological Transition .
A collaboration leaded by INRAE, a research institute working for the coherent and sustainable development of agriculture, food and the environment,
And dedicated to investigations of PFAS soils pollution.
Extreme resolution & sensitivity in FTICRMS
Phase sensitive 2D in absorption mode allows extreme resolution and sensitivity in FTICRMS.
A collaboration between Maria van Agthoven , Katrin Breuker, Marc André Delsuc
Casc4de, IGBMC, University of Strasbourg & Leopold-Franzens Universität Innsbruck.
When quantum computing meets chemistry issue.
Prof Dominique Sugny and Dr Steffen Glaser, OCT specialists from ICB Laboratory, collaborated with Casc4de scientists for a deeper understanding of experimental techniques in analytical sciences.
MASS SPECTROMETRY INNOVATION
CASC4DE, member of the EU FT-ICR MS network, developed a FT-ICR MS software enabling 1D FTICR processing and LC/MS display. Recently we added new features on our tool using original programs :
• the two-dimensional processing 2D-FTICR ,
• analysis of narrow band modulation acquisition increasing resolving power,
• computation of isotopic pattern
🔎 Next to our news, MS spectra from the Glutathione (Evgeny Nikolaev, Skoltech Moscow) and in parallel the simulation of the fine isotopic pattern.
T2 – Inverse Laplace Transform
Explore your porous materials with T-ILT
with an easy and fast
software to analyse your data
FLUOVIAL NMR & ML TECHNIQUES
CASC4DE has developed efficient NMR and Machine Learning techniques for analysis, detection , characterization, quantification and identification of fluorinated compounds (including PFAS pollutants) from NMR spectra.
Automatize your pharmacophoric deconvolution for plant extracts with Plasmodesma.
Fast and intuitive identification of active compounds from natural extracts with an interactive user-friendly graphical web application
CASC4DE, created in 2014 by Marc-André Delsuc and Bruno Kieffer, is a company specialized in the development of analytical methods along with software and data engineering.
CASC4DE develops innovative solutions to tackle the challenges of managing and processing large set of analytical data by combining interdisciplinary skills in the biochemistry, mathematical and data-science fields. Furthermore the company carries out its R&D in the spirit of open science (F.A.I.R. data if possible) and open-source (free and independent software).
CASC4DE also offers services to answer analytical client’s issues. It proposes multi-analytic approaches with access to advanced Nuclear Magnetic Resonance (19F fluorine, 2D, 3D NMR) or Mass Spectrometry (FTICR MS, 2D FTMS).
Biophysics / Analytics
Nuclear Magnetic Resonance
High Res Mass Spectrometry
Custom analytical services
Massive number crunching
Innovative high-speed data processing algorithms and techniques
Custom Software Development
Embeddable packaged software web server
SOFTWARE ENGINEERING, BIG DATA AND SCIENCE
As almost all industrial sectors, science is facing some real data challenges.
Indeed instruments, sensors and pictures collect massive amounts of information and raw data, structured or not. Due to the increasing size of data, current technologies require new approaches for an optimized exploitation ! Computation has to be done where the data is and should to be done locally.
A significant amount of data is generated in real time. Treatment and handling must be performed « on-the-fly », usually without the possibility of archiving the data flow. Moreover, day-to-day datasets are often disparate, noisy and prone to be corrupted by outliers and artefacts. Despite this complexity, our new algorithms, mathematical approaches and methodological techniques allow more robust, faster and automatized data-flows.
Today CASC4DE builds innovative hardware-enhanced capabilities and softwares to accelerate your research and extract hidden insights from your data flow.
USE DATA TO FIND THE ANSWERS YOU ARE LOOKING FOR
Analytical methods Custom Services
CASC4DE offers analytical services including, but not limited to:
– Chemicals Testing
- Routine analyses NMR 1D, 2D, IR, MS for REACH compliance.
- Detection, identification, characterisation and quantification of chemical species, for example:
- small molecules identification (structure elucidation and purity),
- purity control (products quality or security).
– Physico-chemical measurement
- Oxyethylenation degree
- Crosslinking rate.
– Environmental pollutants analysis (fluorinated, PFAS…)
CASC4DE also provides support for analytical methods implementation using:
– Ultra High Resolution Mass Spectrometry FTICR mass analyser (10 to 100 fold higher mass resolving power and accuracy than any other MS techniques)
– NMR spectroscopy applications
Remove the Big Data bottleneck
Speed up your results flow
Dedicated dual expertise
in analytical methods (NMR, High Res MS) and software & data engineering
Technology Solutions created uniquely for Your Needs