Our research publications

CASC4DE is a company specialized in the development of analytical methods along with software and data engineering.

Here are reported our latest publications illustrating some of our research focus areas.

Phase Correction for Absorption Mode Two-Dimensional Mass Spectrometry

M.-A.Delsuc, K. Breuker, M.A. van Agthoven 2021

Molecules, 2021, 26, 3388

Application of Optimal Control Theory to Fourier Transform Ion Cyclotron Resonance

V. Martikyan, C. Beluffi, S.J. Glaser, M.-A. Delsuc, D. Sugny 2021

Molecules, 26, 10: 2860

Phase relationships in two-dimensional mass spectrometry

M. A. van Agthoven, D. P. A. Kilgour, A. M. Lynch, M. P. Barrow, T. E. Morgan, C. A. Wootton, L. Chiron, M.-A. Delsuc, P. B. O’Connor 2019

J. Am. Soc. Mass Spectrom., 30(12) :2594-2607

Deconvolution of isotopic pattern in 2D-FTICR Mass Spectrometry of peptides and proteins

L. Duciel, A. Cherni and M.-A. Delsuc. 2019

Chemical Physics, arXiv:1906.06218

Automatic differential analysis of NMR experiments in complex samples

L. Margueritte, P. Markov, L. Chiron, J.-P. Starck, C. Vonthron Sénécheau, M. Bourjot, and M.-A. Delsuc. 2018

Magn. Reson. Chem., 80(5) :1387

Computing the minimal crew for a multi-generational space journey towards Proxima Centauri b

F. Marin, C. Beluffi 2018

Journal of the British Interplanetary Society, 71, 45-52

Can Two-Dimensional IR-ECD Mass Spectrometry Improve Peptide de Novo Sequencing?

M.A. van Agthoven, A.M. Lynch, T.E. Morgan, C.A. Wootton, Y.P.Y. Lam, L. Chiron, M.P. Barrow, M.-A. Delsuc, and P.B. O’Connor 2018

Anal. Chem. 90, 5, 3496–3504

Bottom-Up Two-Dimensional Electron-Capture Dissociation Mass Spectrometry of Calmodulin

F. Floris, M. A. van Agthoven, L. Chiron, C. A. Wootton, P. Y. Y. Lam, M. P. Barrow, M.-A. Delsuc, and P. B. O’Connor. 2018

J. Am. Soc. Mass Spectrom., 29(1) :207–210

Polymer analysis in the second dimension: preliminary studies for the characterisation of polymers with 2D MS

F. Floris, C. Vallotto, L. Chiron, A. Lynch, M. P. Barrow, M.-A. Delsuc, and P. B. O’Connor. 2017

Anal. Chem., 89(18): 9892-9899

Uncoiling Collagen: A Multidimensional Mass Spectrometry Study

H. J. Simon, M. A. van Agthoven, P. Y. Lam, F. Floris, L. Chiron, M.-A. Delsuc, C. Rolando, M. P. Barrow and P. B. O’Connor. 2016

The Analyst, 141, 157–165

Two-Dimensional Mass Spectrometry for Proteomics, a Comparative Study with Cytochrome c

M. A. van Agthoven, C. A. Wootton, L. Chiron, M. A. Coutouly, A. Soulby, J. Wei et al 2016

Anal. Chem., 88(8): 4409–4417

Narrowband Modulation Two-Dimensional Mass Spectrometry and Label-Free Relative Quantification of Histone Peptides

M. Halper, M.-A. Delsuc, K. Breuker, and M.A. van Agthoven 2020

Anal. Chem., 92, 20, 13945–13952

Automatised Pharmacophoric Deconvolution of Plant Extracts, application to Cinchona bark crude extract

L. Margueritte, L. Duciel, M. Bourjot, C. Vonthron-Sénécheau and M.-A. Delsuc 2019

Faraday Discussions, 218, 441-458

Two-dimensional mass spectrometry: new perspectives for tandem mass spectrometry

M. A. van Agthoven, Y. P. Y. Lam, P. B. O’Connor, C. Rolando & M.-A. Delsuc. 2019

European Biophysics Journal, 48 :213–229

Application of Tandem Two-Dimensional Mass Spectrometry for Top-Down Deep Sequencing of Calmodulin

F. Floris, L. Chiron, A. Lynch, M. P. Barrow, M.-A. Delsuc, and P. B. O’Connor. 2018

J. Am. Soc. Mass Spectrom., 29 :1700–1705

Top-Down Deep Sequencing of Ubiquitin using two-dimensional mass spectrometry

F. Floris, L. Chiron, A. Lynch, M. P. Barrow, M.-A. Delsuc, and P. B. O’Connor. 2018

Anal. Chem., 90(12) :7302–7309

Numerical constraints on the size of generation ships from total energy expenditure on board, annual food production and space farming techniques

F. Marin, C. Beluffi, R. Taylor, L. Grau 2018

Journal of the British Interplanetary Society, 71, 382

2D FT-ICR MS of Calmodulin: A Top-Down and Bottom-Up Approach

F. Floris, M. van Agthoven, L. Chiron, et al. 2016

J. Am. Soc. Mass Spectrom., 27(9): 1531–1538

SPIKE a Processing Software dedicated to Fourier Spectroscopies

L. Chiron, M.-A. Coutouly, J.-P. Starck, C. Rolando, M.-A. Delsuc. 2016

arXiv 1608.06777

Efficient denoising algorithms for large experimental datasets and their applications in Fourier transform ion cyclotron resonance mass spectrometry

L. Chiron, M. A. van Agthoven, B. Kieffer, C. Rolando, and M-A. Delsuc. 2014

PNAS 111(4): 1385-1390